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Main Title: Design and Fabrication of a BiCMOS Dielectric Sensor for Viscosity Measurements: A Possible Solution for Early Detection of COPD
Author(s): Soltani Zarrin, Pouya
Jamal, Farabi Ibne
Guha, Subhajit
Wessel, Jan
Kissinger, Dietmar
Wenger, Christian
Type: Article
Language Code: en
Abstract: The viscosity variation of sputum is a common symptom of the progression of Chronic Obstructive Pulmonary Disease (COPD). Since the hydration of the sputum defines its viscosity level, dielectric sensors could be used for the characterization of sputum samples collected from patients for early diagnosis of COPD. In this work, a CMOS-based dielectric sensor for the real-time monitoring of sputum viscosity was designed and fabricated. A proper packaging for the ESD-protection and short-circuit prevention of the sensor was developed. The performance evaluation results show that the radio frequency sensor is capable of measuring dielectric constant of biofluids with an accuracy of 4.17%. Integration of this sensor into a portable system will result in a hand-held device capable of measuring viscosity of sputum samples of COPD-patients for diagnostic purposes.
Issue Date: 21-Aug-2018
Date Available: 11-Sep-2019
DDC Class: 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
Subject(s): Sputum–Mucin
dielectric measurements
CMOS viscosity sensor
radio frequency sensor
precision diagnostics
Sponsor/Funder: BMBF, 13N13862, POC-Sensorplattform für chronisch-entzündliche Atemwegserkrankungen (EXASENS) - On-Chip-CMOS-Sensorik
Journal Title: Biosensors
Publisher: MDPI
Publisher Place: Basel
Volume: 8
Issue: 3
Article Number: 78
Publisher DOI: 10.3390/bios8030078
EISSN: 2079-6374
Appears in Collections:Inst. Hochfrequenz- und Halbleiter-Systemtechnologien » Publications

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