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Main Title: Recent Progress in Optical Sensors for Biomedical Diagnostics
Author(s): Pirzada, Muqsit
Altintas, Zeynep
Type: Article
Language Code: en
Abstract: In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of different detection mechanisms. Such conjugated sensing platforms facilitate the exploitation of their neoteric synergistic characteristics for sensor fabrication. This paper covers nearly 250 research articles since 2016 representing the emerging interest in rapid, reproducible and ultrasensitive assays in clinical analysis. Therefore, we present an elaborate review of biomedical diagnostics with the help of optical sensors working on varied principles such as surface plasmon resonance, localised surface plasmon resonance, evanescent wave fluorescence, bioluminescence and several others. These sensors are capable of investigating toxins, proteins, pathogens, disease biomarkers and whole cells in varied sensing media ranging from water to buffer to more complex environments such as serum, blood or urine. Hence, the recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices.
Issue Date: 30-Mar-2020
Date Available: 12-May-2020
DDC Class: 534 Schall und verwandte Schwingungen
Subject(s): optical sensors
biomedical diagnostics
surface plasmon resonance
evanescent wave
surface enhanced Raman scattering
reflectometric interference spectroscopy
Sponsor/Funder: DFG, 428780268, Biomimetische Rezeptoren auf NanoMIP-Basis zur Virenerkennung und -entfernung mittels integrierter Ansätze
Journal Title: Micromachines
Publisher: MDPI
Publisher Place: Basel
Volume: 11
Issue: 4
Article Number: 356
Publisher DOI: 10.3390/mi11040356
EISSN: 2072-666X
Appears in Collections:FG Mehrphasenreaktionstechnik » Publications

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