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Main Title: Analysis of DNA Sequence Variation within Marine Species Using Beta-Coalescents
Author(s): Birkner, Matthias
Blath, Jochen
Steinrücken, Matthias
Type: Research Paper
Abstract: We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit shallow gene genealogies, potentially due to extreme reproductive behaviour, e.g. via Hedgecock's "reproduction sweepstakes". Besides the data analysis, in particular the inference of mutation rates and the estimation of the (real) time to the most recent common ancestor, we briefly address the question whether the genealogies might be adequately described by so-called Beta coalescents (as opposed to Kingman coalescents), allowing multiple mergers of genealogies. The choice of the underlying coalescent model for the genealogy has drastic implications for the estimation of the above quantities, in particular the real-time embedding of the genealogy.
Subject(s): Beta-coalescents
inference of mutation rates
time to the most recent common ancestor
hedgecock sweepstakes
population genetics
Issue Date: 18-Feb-2011
Date Available: 17-Dec-2021
Language Code: en
DDC Class: 510 Mathematik
MSC 2000: 62F99 None of the above, but in this section
62P10 Applications to biology and medical sciences
92D10 Genetics
92D20 Protein sequences, DNA sequences
Series: Preprint-Reihe des Instituts für Mathematik, Technische Universität Berlin
Series Number: 2011, 04
ISSN: 2197-8085
TU Affiliation(s): Fak. 2 Mathematik und Naturwissenschaften » Inst. Mathematik
Appears in Collections:Technische Universität Berlin » Publications

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