Fachgebiet Nanostrukturierte Biomaterialien

8 Items

Recent Submissions
Nano-contact transfer with gold nanoparticles on PEG hydrogels and using wrinkled PDMS-stamps

Yesildag, Cigdem ; Tyushina, Arina ; Lensen, Marga C. (2017)

In the present work, a soft lithographic process is used to create nanometer-sized line patterns of gold nanoparticles (Au NPs) on PEG-based hydrogels. Hereby nanometer-sized wrinkles on polydimethylsiloxane (PDMS) are first fabricated, then functionalized with amino-silane and subsequently coated with Au NPs. The Au NPs are electrostatically bound to the surface of the wrinkled PDMS. In the ne...

Novel wet micro-contact deprinting method for patterning gold nanoparticles on PEG-hydrogels and thereby controlling cell adhesion

Yesildag, Cigdem ; Bartsch, Christoph ; Vicente, Gonzalo de ; Lensen, Marga C. (2017)

In the present work we introduce a novel method to create linear and rectangular micro-patterns of gold nanoparticles (Au NPs) on poly(ethylene glycol) (PEG) hydrogels. The strategy consists of removing Au NPs from defined regions of the silicon wafer by virtue of the swelling effect of the hydrogel. Using this method, which we denote as “Wet Micro-Contact Deprinting”, well-defined micro-patter...

Synthesis of gold nanoparticle-hydrogel nanocomposites with controlled cytotoxicity and unique cell-adhesive properties

Ren, Fang (2016)

Gold Nanopartikeln (Au NPs) spielen eine bedeutende Rolle in Chemie, Biologie, Ingenieurwesen und Medizin aufgrund ihrer einzigartigen optischen Eigenschaften, leichten Synthese und Flexibilitat in der (bio)chemischen Funktionalisierung. Kenntnis über ihre potentielle Toxizität ist notwendig bevor diese Nanomaterialien in realen klinischen Einstellungen angewendet werden, insbesondere wenn sie ...

Synthesis of nano-scale materials through miniemulsion polymerization method and their application in textiles

Elgammal, Mahmoud (2016)

The present work deals with the preparation of nanosized copolymer latexes by the polymerization in miniemulsions prepared by the classical high energy and the low energy phase inversion concentration (PIC) methods. In addition, the encapsulation of various organic pigments with copolymer latex layers was carried out on the basis of miniemulsion polymerization. The obtained nanosized copolymer ...

Hybrid hierarchical patterns of gold nanoparticles and poly(ethylene glycol) microstructures

Chen, Jingyu ; Arafeh, Manar ; Guiet, Amandine ; Felkel, Diana ; Loebus, Axel ; Kelleher, Susan M. ; Fischer, Anna ; Lensen, Marga C. (2013)

Hybrid surface micro-patterns composed of topographic structures of polyethylene glycol (PEG)-hydrogels and hierarchical lines of gold nanoparticles (Au NPs) were fabricated on silicon wafers. Micro-sized lines of Au NPs were first obtained on the surface of a silicon wafer via “micro-contact deprinting”, a method recently developed by our group. Topographic micro-patterns of PEG, of both low a...

Cell phenotypic changes of mouse connective tissue fibroblasts (L-929) to poly(ethylene glycol)-based gels

Strehmel, Christine ; Zhang, Zhenfang ; Strehmel, Nadine ; Lensen, Marga C. (2013)

Cellular responses to various gels fabricated by photoinitiated crosslinking using acrylated linear and multi-arm poly(ethylene glycol) (PEG)-based and poly(propylene glycol)-b-poly(ethylene glycol) precursors were investigated. While no protein adsorption and cell adhesion were observed on the hydrophilic PEG-based gels, protein adsorption and cell adhesion did occur on the more hydrophobic ge...

Blending PEG-based polymers and their use in surface micro-patterning by the FIMIC method to obtain topographically smooth patterns of elasticity

Kelleher, S. M. ; Zhang, Z. ; Löbus, A. ; Strehmel, C. ; Lensen, M. C. (2014)

We have designed and fabricated a library of polyethylene glycol (PEG)-based polymer blends, including blends of two PEG-based polymers that are liquid at room temperature where the optimisation of the blending method allows for the incorporation of higher molecular-weight PEG-based polymers which are solid at room temperature. The absence of a solvent in these blends makes them perfect candida...

In situ crystal growth of zeolitic imidazolate frameworks (ZIF) on electrospun polyurethane nanofibers

Zhou Lian ; Lu Huimin ; Ouyang Zhaofei (2014)

This paper reports for the first time in situcrystal growth of ZIF-8 on electrospun polyurethane (PU) nanofibers. In SEM images, continuous and compact ZIF-8 nanocrystals grow along electrospun PU nanofibers. The highest loading capacity of ZIF-8 on PU reaches 63%. By N2adsorption–desorption, ZIF-8-PU shows a high surface area of 566 cm2g−1. Combining the good flexibility of PU with the high ad...