Richter, Lennart; Wanka, Franziska; Boecker, Simon; Storm, Dirk; Kurt, Tutku; Vural, Özlem; Süßmuth, Roderich; Meyer, Vera (2014)
Background: Filamentous fungi can each produce dozens of secondary metabolites which are attractive as therapeutics, drugs, antimicrobials, flavour compounds and other high-value chemicals. Further...Tet-on, or tet-off, that is the question: advanced conditional gene expression in Aspergillus
Wanka, Franziska; Cairns, Timothy; Boecker, Simon; Berens, Christian; Happel, Anna; Zheng, Xiaomei; Sun, Jibin; Krappmann, Sven; Meyer, Vera (2016)
In Aspergillus, controlled gene expression is often achieved using the reverse tetracycline-controlled transactivator (rtTA) dependent Tet-on system, whereby transcription is activated in a titrata...Gen- und verfahrenstechnische Ansätze zur Optimierung von Aspergillus niger als Expressionsplattform
Wanka, Franziska (2016)
Aspergillus niger has the ability to synthesise large amounts of acids and proteins, and to secrete these into the environment. This particular property is used in biotechnology to produce platform...