Fak. 3 Prozesswissenschaften

1151 Items

Recent Submissions
Mobile multi-parameter measurements for the dynamic analysis of gradients in brewing vessels

Bockisch, Anika (2018)

Industrial processes have to be competitive and thus efficient. Products have to be produced with a high reproducibility and quality. At the same time, the scale of these processes reaches up to several 100 m³ and was even increasing in recent years. This is challenging since the power input is limited in large-scale processes. Therefore, mixing times are increasing in parallel to the volume, w...

Entwicklung eines Frühwarnsystems zur Steigerung der Raum-Zeit-Ausbeute einstufiger NawaRo-Biogasanlagen durch Additivzugabe

Schröder, Patrick (2018)

Zur Steigerung der Raum-Zeit-Ausbeute in einstufigen, landwirtschaftlichen Biogasanlagen wurden Versuche zur Entwicklung von Frühwarnindikatoren (FWI) für Prozessstörungen und von Maßnahmen zur Prozessstabilisierung, sowie zur Substratzusammensetzung durchgeführt. Ein neuer FWI wurde entwickelt, der A/elCon, das Verhältnis aus der Konzentration organischer Säuren (engl.: org. acids) zur elektr...

Towards the colonization of Mars by in-situ resource utilization: Slip cast ceramics from Martian soil simulant

Karl, David ; Kamutzki, Franz ; Zocca, Andrea ; Görke, Oliver ; Günster, Jens ; Gurlo, Aleksander (2018-10-11)

Here we demonstrate that by applying exclusively Martian resources a processing route involving suspensions of mineral particles called slurries or slips can be established for manufacturing ceramics on Mars. We developed water-based slurries without the use of additives that had a 51 wt. % solid load resembling commercial porcelain slurries in respect to the particle size distribution and rheo...

In silico prediction and characterization of secondary metabolite biosynthetic gene clusters in the wheat pathogen Zymoseptoria tritici

Cairns, Timothy ; Meyer, Vera (2017-08-17)

Background Fungal pathogens of plants produce diverse repertoires of secondary metabolites, which have functions ranging from iron acquisition, defense against immune perturbation, to toxic assaults on the host. The wheat pathogen Zymoseptoria tritici causes Septoria tritici blotch, a foliar disease which is a significant threat to global food security. Currently, there is limited knowledge of...

Polycistronic gene expression in Aspergillus niger

Schütze, Tabea ; Meyer, Vera (2017-09-25)

Background Genome mining approaches predict dozens of biosynthetic gene clusters in each of the filamentous fungal genomes sequenced so far. However, the majority of these gene clusters still remain cryptic because they are not expressed in their natural host. Simultaneous expression of all genes belonging to a biosynthetic pathway in a heterologous host is one approach to activate biosyntheti...

Comparative evaluation of methanol production processes using natural gas

Blumberg, Timo Dominik (2018)

In the work, different processes for the production of methanol from natural gas are analysed from a thermodynamic and an economic point of view. Commercially available processes and promising future alternatives for increased thermodynamic efficiency, improved economics and reduced greenhouse gas emissions are assessed and compared. The analysed processes are based on the indirect synthesis ro...

Möglichkeiten und Grenzen von Modellstoffsystemen zur hydrodynamischen Charakterisierung zentral gerührter Biogasanlagen

Altwasser, Sebastian (2018)

Aufgrund der gesetzlichen Rahmenbedingungen und des verstärkten Auftreten von Rührwerksausfällen in Biogasanlagen sind viele Firmen, die sich auf den Bau und die Inbetriebnahme von Biogasanlagen spezialisiert haben, gezwungen an den derzeitigen Bestandsanlagen umfangreiche Repowering-Maßnahmen durchzuführen. Oftmals gibt es jedoch nur sehr wenige oder gar keine Kenntnisse zur Hydrodynamik in so...

Accelerated Bioprocess Development of Endopolygalacturonase-Production with Saccharomyces cerevisiae Using Multivariate Prediction in a 48 Mini-Bioreactor Automated Platform

Sawatzki, Annina ; Hans, Sebastian ; Narayanan, Harini ; Haby, Benjamin ; Krausch, Niels ; Sokolov, Michael ; Glauche, Florian ; Riedel, Sebastian L. ; Neubauer, Peter ; Cruz Bournazou, Mariano Nicolas (2018-11-21)

Mini-bioreactor systems enabling automatized operation of numerous parallel cultivations are a promising alternative to accelerate and optimize bioprocess development allowing for sophisticated cultivation experiments in high throughput. These include fed-batch and continuous cultivations with multiple options of process control and sample analysis which deliver valuable screening tools for ind...

Phthalocyanine-fullerene dyads and DNA interstrand cross-linking on surface

Véliz Montes, Cinthya Yamila (2018)

Nanotechnology deals with structures and components of nanoscale size in order to create new properties or to improve significantly their physical, chemical and biological properties, processes and phenomena. Many efforts of molecular nanotechnology are directed to design artificial nanostructures on surfaces due to their potential applications in nanodevices and biosensors. This thesis include...

Studies on the Biosynthesis of γ–Decalactone in Sporobolomyces odorus

Albrecht, Wolfgang ; Tressl, Roland (1990)

Incubation of racemic ethyl [2,2-2H2]-(E)-3,4-epoxydecanoate and the corresponding acid with intact cells of Sporobolomyces odorus led to the formation of deuterium labeled γ-decalaetone. The detection of labeled 2-decen-4-olide and 4-oxodecanoic acid made it possi­ble to propose the biogenetic sequence leading to γ-decalactone. The determination of the en­ antiomeric ratio of the lactone revea...

Innovative Anwendungen von polymeren Werkstoffen in der Medizintechnik

Müller, Th. ; Käufer, H. (1998)

Das bekannte Prinzip des Kunststoff-Schrumpfschlauches, der bei etwa 120°C eine Formänderung vollzieht, wurde vom Fachgebiet Polymertechnik der TU-Berlin in der Art weiterentwickelt, daß es möglich ist, schon eine Formänderung eines Teiles bei Temperaturen zu erreichen, die im menschlichen Organismus vorliegen können.

Einfluß von Sterilisationsverfahren auf thermoplastische Kunststoffe unter spezieller Berücksichtigung modifizierter Oberflächen

Müller, Thomas ; Käufer, Helmut (1999)

Für Werkstoffe für den Einsatz im Medikalbereich ist die Sterilisationsfähigkeit unabdingbare Voraussetzung. Die gängigen Sterilisationsmethoden rufen bei den meisten polymeren Werkstoffen Veränderungen hervor, die bis hin zur Spaltung der Polymerketten führen können. Speziell die in dieser Arbeit untersuchten, zur Verbesserung der Biokompatibilität modifizierten Oberflächen, die durch ihre sta...

Generation of a 3D Liver Model Comprising Human Extracellular Matrix in an Alginate/Gelatin-Based Bioink by Extrusion Bioprinting for Infection and Transduction Studies

Hiller, Thomas ; Berg, Johanna ; Elomaa, Laura ; Röhrs, Viola ; Ullah, Imran ; Schaar, Katrin ; Dietrich, Ann-Christin ; Al-Zeer, Munir A. ; Kurtz, Andreas ; Hocke, Andreas C. ; Hippenstiel, Stefan ; Fechner, Henry ; Weinhart, Marie ; Kurreck, Jens (2018-10-12)

Bioprinting is a novel technology that may help to overcome limitations associated with two-dimensional (2D) cell cultures and animal experiments, as it allows the production of three-dimensional (3D) tissue models composed of human cells. The present study describes the optimization of a bioink composed of alginate, gelatin and human extracellular matrix (hECM) to print human HepaRG liver cell...

Conditioning fixed-bed filters with fine fractions of granulated iron hydroxide (µGFH)

Hilbrandt, Inga ; Ruhl, Aki S. ; Jekel, Martin (2018-09-25)

The fine fraction of granular ferric hydroxide (µGFH, <0.3 mm) is a promising adsorbent for the removal of heavy metals and phosphate, but properties of µGFH were hitherto not known. The present study aimed at characterizing µGFH regarding its physical and chemical properties and at evaluating methods for the conditioning of fixed-bed filters in order to develop a process that combines filtrati...

The Changes in the Lipid Composition of Mung Bean Seeds as Affected by Processing Methods

Abdel-Rahman, El-Sayed Ali ; El-Fishawy, Fawzy A. ; El-Geddawy, Mohamed A. ; Kurz, Tomas ; El-Rify, Mohamed N. (2007)

This study was conducted to assess in detail the possible effects of some technological processes such as soaking, germination, cooking, soaking + cooking, and germination + cooking on the lipid composition of mung bean seeds of Giza 1 variety. TLC analysis of mung bean lipids showed that the phospholipids and triglycerides recorded the highest percentage among lipid fractions (32.26 and 30.10%...

Simplified Kinetics and Colour Formation in Sucrose Solutions Based on A-Dicarbonyl Compounds

Smejkal, Quido ; Fiedler, Thorsten ; Kurz, Tomas ; Kroh, Lothar (2007)

Colour formation in technical and model sucrose solutions was investigated resulting in a novel kinetic approach of MAILLARD reaction during thermal processing of sugar solutions. Presented results describe new aspects of the non-enzymatic browning reaction (MAILLARD reaction). Two temperature depending pathways of colour formation were found. Both reaction mechanisms are based on the formation...

Experimentelle Analyse und Modellierung des Stofftransportes durch Kohlenstoffmembranen bei der Hochdruckgastrennung

Kruse, Nicolas (2018)

Obwohl die Gastrennung mit Kohlenstoffmembranen mittlerweile ein etabliertes Gebiet der Membranforschung darstellt und Kohlen-stoffmembranen generell geeignet für den Einsatz unter Hochdruckbedingungen sind, liegen bisher nur wenige Veröffentlichungen zur Untersuchung ihres Trennverhaltens oberhalb von 2 MPa vor. Auch die etablierten Stofftransportmodelle zur Beschreibung von porösen Membranen ...

Analysis of metabolic pathways controlling cAMP-regulated aquaporin-2 trafficking in renal principal cells

Schulz, Maike (2018)

One of the main effectors of the second messenger cyclic adenosine monophosphate (cAMP) is the ubiquitously expressed serine/threonine protein kinase, cAMP-dependent protein kinase (PKA). Binding of cAMP to the regulatory subunits of PKA results in a conformational change and the release of the catalytic subunits to phosphorylate nearby targets. To ensure spatially and temporally controlled pho...

The Sustainable Child Development Index (SCDI)

Chang, Ya-Ju (2018)

Children and sustainable development are mutually supporting to each other. However, children are not widely addressed in existing sustainability assessments. The disregard of children in sustainability assessments can lead to incomplete evaluation of sustainable development. In addition, current children related studies have not yet considered topics with regard to sustainable development with...

Entwicklung und Validierung eines Prüfverfahrens zur Bestimmung der Radon-222-Exhalationsrate aus Bauprodukten in VOC-Emissionsprüfkammern

Hofmann, Michael (2018)

This doctoral thesis describes the development and validation of a practical test procedure for the determination of the radon-222 exhalation rate from building materials under simulated indoor conditions. To ensure practical relevance, the test procedure is based on standardised and validated methods for the determination of emission of volatile organic compounds (VOC) from materials in emissi...