Fak. 3 Prozesswissenschaften

1878 Items

Recent Submissions
Nutritive Manganese and Zinc Overdosing in Aging C. elegans Result in a Metallothionein‐Mediated Alteration in Metal Homeostasis

Baesler, Jessica ; Michaelis, Vivien ; Stiboller, Michael ; Haase, Hajo ; Aschner, Michael ; Schwerdtle, Tanja ; Sturzenbaum, Stephen R. ; Bornhorst, Julia (2021-03-09)

Scope Manganese (Mn) and zinc (Zn) are not only essential trace elements, but also potential exogenous risk factors for various diseases. Since the disturbed homeostasis of single metals can result in detrimental health effects, concerns have emerged regarding the consequences of excessive exposures to multiple metals, either via nutritional supplementation or parenteral nutrition. This study ...

Editorial: Continuous Biomanufacturing in Microbial Systems

Herwig, Christoph ; Slouka, Christoph ; Neubauer, Peter ; Delvigne, Frank (2021-06-07)

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Optimization of the Indirect Extrusion Process of Copper-Clad Aluminum Rods by Methods of Statistical Experimental Designs and Numerical Analyses

Lechner, Stefan ; Rœmisch, Ute ; Nitschke, René ; Gensch, Felix ; Mueller, Soeren (2021-05-13)

The success of composite extrusion is influenced by multiple process parameters. In order to investigate the significance of specific parameters during indirect extrusion of copper-clad aluminum (CCA) rods, statistical methods were applied and a central composite experimental design was implemented. The runs of the experimental design were modeled with the finite element method based software D...

Untersuchung von triazin-basierten polybromierten Flammschutzmitteln

Lörchner, Dominique (2021)

Polybromierte Flammschutzmittel (PBFSM) umfassen strukturell verschiedene Verbindungen, die zur Reduzierung der Entflammbarkeit von Polymeren eingesetzt werden. Aufgrund ihrer globalen Verteilung, möglichen Persistenz, Bioakkumulation und Toxizität sind frühere Vertreter der PBFSM u. a. in der Europäischen Union teilweise verboten oder eingeschränkt nutzbar. Daher wurden die Verbindungen z. T. ...

Influence of the protein structure on the stabilization of oil/water-interfaces

Kieserling, Helena (2021)

Food products based on oil/water-emulsions, such as beverages, dairy products, or targeted delivery systems for functional food ingredients, are thermodynamically unstable systems. Over time, on a macro-level, the dispersed oil droplets in the water phase tend to flocculate, coalesce, and cream. The kinetics of these destabilization mechanisms depend on the emulsifier properties on the micro-le...

Analytical methods and thermodynamic frameworks for efficient biocatalytic nucleoside synthesis via nucleoside phosphorylases

Kaspar, Felix (2021)

Nucleosides and nucleoside analogs are indispensable biomolecules which serve as buildings blocks of DNA and RNA, pharmaceuticals and molecular biology tools. Sparked by the demand for synthetic access to these compounds, a variety of approaches for nucleoside synthesis has been developed. Among these, biocatalytic nucleoside synthesis via nucleoside phosphorylases promises a solution to the lo...

Retention time prediction using neural networks increases identifications in crosslinking mass spectrometry

Giese, Sven H. ; Sinn, Ludwig R. ; Wegner, Fritz ; Rappsilber, Juri (2021-05-28)

Crosslinking mass spectrometry has developed into a robust technique that is increasingly used to investigate the interactomes of organelles and cells. However, the incomplete and noisy information in the mass spectra of crosslinked peptides limits the numbers of protein–protein interactions that can be confidently identified. Here, we leverage chromatographic retention time information to aid ...

Advancing the water footprint into an instrument to support achieving the SDGs – Recommendations from the “Water as a Global Resources” Research Initiative (GRoW)

Berger, Markus ; Campos, Jazmin ; Carolli, Mauro ; Dantas, Ianna ; Forin, Silvia ; Kosatica, Ervin ; Kramer, Annika ; Mikosch, Natalia ; Nouri, Hamideh ; Schlattmann, Anna ; Schmidt, Falk ; Schomberg, Anna ; Semmling, Elsa (2021-03-04)

The water footprint has developed into a widely-used concept to examine water use and resulting local impacts caused during agricultural and industrial production. Building on recent advancements in the water footprint concept, it can be an effective steering instrument to support, inter alia, achieving sustainable development goals (SDGs) - SDG 6 in particular. Within the research program “Wat...

3D bioprinting of tissue-specific osteoblasts and endothelial cells to model the human jawbone

Amler, Anna-Klara ; Thomas, Alexander ; Tüzüner, Selin ; Lam, Tobias ; Geiger, Michel-Andreas ; Kreuder, Anna-Elisabeth ; Palmer, Chris ; Nahles, Susanne ; Lauster, Roland ; Kloke, Lutz (2021-03-01)

Jawbone differs from other bones in many aspects, including its developmental origin and the occurrence of jawbone-specific diseases like MRONJ (medication-related osteonecrosis of the jaw). Although there is a strong need, adequate in vitro models of this unique environment are sparse to date. While previous approaches are reliant e.g. on scaffolds or spheroid culture, 3D bioprinting enables f...

Bracket fungi, natural lightweight construction materials: hierarchical microstructure and compressive behavior of Fomes fomentarius fruit bodies

Müller, Cecilia ; Klemm, Sophie ; Fleck, Claudia (2021-02-10)

Bracket fungi such as Fomes fomentarius (“tinder fungus”), have strong, light and tough fruit bodies that make them interesting role-models for bio-inspired, biodegradable applications. So far, little is known about the relation between their microstructure and mechanical properties, information needed for designing novel composites. The fruit bodies (mycelia) of tinder fungus are hierarchicall...

Development of a targeted HPLC-ESI-QqQ-MS/MS method for the quantification of sulfolipids from a cyanobacterium, selected leafy vegetables, and a microalgae species

Fischer, Judith ; Treblin, Mascha ; Sitz, Tobias ; Rohn, Sascha (2021-01-22)

The use of macro- and microalgae, as well as cyanobacteria, becomes increasingly important for human nutrition, even in Western diets. Health effects, positive as well as negative, are believed to result mainly from minor components in the food. In macro- and microalgae as well as in certain cyanobacteria, one class of such minor compounds is sulfolipids, more precisely sulfoquinovosylmonoacylg...

Digitalisierung in der Energiewirtschaft

Corusa, Andreas ; Erdmann, Georg ; Timofeeva, Elena ; Predel, Johannes Norbert ; Ritschel, Falk ; Sprengel, Christian ; Walther, Anne ; Kaufmann, Daniel ; Brühl, Stefan ; Stocker, Victor ; Rosinger, Christine ; Uslar, Mathias ; Schäfer-Stradowski, Simon (2021-05)

Wir unternehmen mit diesem Werk den Versuch einen Teil der Komplexität des Themas anhand des Knowhows der beitragenden Autoren aus verschiedenen Disziplinen zu vereinen, um nicht nur Neugier des Lesenden zu wecken, sondern auch und um über das Thema Digitalisierung aufzuklären. Dabei besteht das Kompendium aus vier Teilen, die verschieden Herausforderungen der Digitalisierung beleuchten und sys...

Life cycle assessment of decarbonization options—towards scientifically robust carbon neutrality

Finkbeiner, Matthias ; Bach, Vanessa (2021-04-01)

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The First City Organizational LCA Case Study: Feasibility and Lessons Learned from Vienna

Cremer, Alexander ; Berger, Markus ; Müller, Katrin ; Finkbeiner, Matthias (2021-04-30)

Cities are recognized as a major contributor to environmental pressures. Recently, organizational LCA (OLCA) has been found to align well with requirements for city-scale environmental decision support and a novel city-OLCA framework was introduced. City-OLCA combines two relevant aspects: It covers activities beyond public service provision (multi-stakeholder) and emissions beyond greenhouse g...

Relationship between Phenolic Compounds, Antioxidant Properties, and the Allergenic Protein Mal d 1 in Different Selenium-Biofortified Apple Cultivars (Malus domestica)

Groth, Sabrina ; Budke, Christoph ; Weber, Timo ; Neugart, Susanne ; Brockmann, Sven ; Holz, Martina ; Sawadski, Bao Chau ; Daum, Diemo ; Rohn, Sascha (2021-04-30)

Notable parts of the population in Europe suffer from allergies towards apples. To address this health problem, the analysis of the interactions of relevant allergens with other substances such as phenolic compounds is of particular importance. The aim of this study was to evaluate the correlations between the total phenolic content (TPC), polyphenol oxidase (PPO) activity, antioxidant activity...

Influence of Macroscopic Wall Structures on the Fluid Flow and Heat Transfer in Fixed Bed Reactors with Small Tube to Particle Diameter Ratio

Eppinger, Thomas ; Jurtz, Nico ; Kraume, Matthias (2021-04-14)

Fixed bed reactors are widely used in the chemical, nuclear and process industry. Due to the solid particle arrangement and its resulting non-homogeneous radial void fraction distribution, the heat transfer of this reactor type is inhibited, especially for fixed bed reactors with a small tube to particle diameter ratio. This work shows that, based on three-dimensional particle-resolved discrete...

Co-Digestion of Rice Straw with Cow Manure in an Innovative Temperature Phased Anaerobic Digestion Technology: Performance Evaluation and Trace Elements

Muhayodin, Furqan ; Fritze, Albrecht ; Larsen, Oliver Christopher ; Spahr, Marcel ; Rotter, Vera Susanne (2021-04-29)

Rice straw is an agricultural residue produced in abundant quantities. Open burning and plowing back the straw to the fields are common practices for its disposal. In-situ incorporation and burning cause emissions of greenhouse gas and particulate matter. Additionally, the energy potential of rice straw is lost. Anaerobic digestion is a technology that can be potentially used to utilize the sur...

The Nonribosomal Peptide Valinomycin: From Discovery to Bioactivity and Biosynthesis

Huang, Shuhui ; Liu, Yushi ; Liu, Wan-Qiu ; Neubauer, Peter ; Li, Jian (2021-04-08)

Valinomycin is a nonribosomal peptide that was discovered from Streptomyces in 1955. Over the past more than six decades, it has received continuous attention due to its special chemical structure and broad biological activities. Although many research papers have been published on valinomycin, there has not yet been a comprehensive review that summarizes the diverse studies ranging from struct...

Biogas Plants in Renewable Energy Systems—A Systematic Review of Modeling Approaches of Biogas Production

Heiker, Mathias ; Kraume, Matthias ; Mertins, Anica ; Wawer, Tim ; Rosenberger, Sandra (2021-04-08)

Biogas production is a relevant component in renewable energy systems. The paper addresses modeling approaches from an energy system, as well as from a process optimization, point of view. Model approaches of biogas production show different levels of detail. They can be classified as white, gray, and black box, or bottom-up and top-down approaches. On the one hand, biogas modeling can supply d...

Assessment of Analytical Orientation Prediction Models for Suspensions Containing Fibers and Spheres

Dietemann, Bastien ; Bosna, Fatih ; Kruggel-Emden, Harald ; Kraft, Torsten ; Bierwisch, Claas (2021-04-13)

Analytical orientation models like the Folgar Tucker (FT) model are widely applied to predict the orientation of suspended non-spherical particles. The accuracy of these models depends on empirical model parameters. In this work, we assess how well analytical orientation models can predict the orientation of suspensions not only consisting of fibers but also of an additional second particle typ...