Frenzel, Falko (2017-11)
Die Entdeckung einer Vielzahl an Produkten der Maillard-Reaktion und Lipidoxidation in einem breiten Spektrum an zubereiteten Lebensmitteln wie etwa Grillgut, Kaffee, Pflanzenölen und erhitztem Getreide setzte die behördlichen Verbraucherschützer unter Druck. In Ermangelung hinreichender Daten zu toxikologischen Eigenschaften ist eine adäquate Risikobewertung für viele hitzebedingte Lebensmitte...Studien zur endogenen Expression von RNA G-Quadruplexen und deren Interaktion mit zellulären Proteinen
Serikawa, Tatsuo (2017)
Due to specific orientation of guanine molecules certain guanine-rich sequences can form inter- or intramolecular structures, known as Guanine (G)-quadruplexes (G4s or GQs). Over the last 10 years, it has been shown several times that RNA G-quadruplexes located in the 5´ UTR of the mRNA suppress translation, however, a recent study indicated that in eukaryotic cells RNA G-quadruplexes are globa...Etablierung eines dreidimensionalen Infektionsmodells für Kuhpockenviren in humaner Haut und Charakterisierung der Infektion
Neumann, Markus (2017)
Heutzutage stehen dreidimensionale Zellkulturmodelle für verschiedenste Anwendungen und Organe, z. B. die Haut, zur Verfügung. Für die Untersuchung viraler Infektionen bietet die Nutzung von 3D-Modellen eine wichtige physiologische Alternative, da die Organoide die Lücke zwischen Studien in klassischer 2D-Zellkultur und im Tiermodell schließen können. Im Rahmen dieser Studie werden die zoonotis...Potentials and Barriers for Tantalum Recovery from Waste Electric and Electronic Equipment
Ueberschaar, Maximilian ; Jalalpoor, Daniel Dariusch ; Korf, Nathalie ; Rotter, Vera Susanne (2017)
Circular economy approaches aim to close material cycles along the value chain. As such, the circular economy can be a long-term strategy to mitigate the risks of critical raw material (CRM) supply. Tantalum, with a current end-of-life recycling rate of less than 1%, has been intermittently discussed as critical. Even though the specificity of tantalum applications and high-mass fractions of ta...Enabling the recycling of rare earth elements through product design and trend analyses of hard disk drives
Ueberschaar, Maximilian ; Rotter, Vera Susanne (2015)
Hard disk drives consist of a complex mix of various materials. While Aluminum, Copper and Steel are easy to separate, actual recycling processes dilute containing rare earth elements to non-recoverable grades in other material streams. To enable future recycling of these materials an in-depth analysis of hard disk drives from Desktop PCs and Notebooks was carried out. Furthermore, possible rec...Challenges for critical raw material recovery from WEEE
Ueberschaar, Maximilian ; Otto, Sarah Julie ; Rotter, Vera Susanne (2017)
Gallium and gallium compounds are more frequently used in future oriented technologies such as photovoltaics, light diodes and semiconductor technology. In the long term the supply risk is estimated to be critical. Germany is one of the major primary gallium producer, recycler of gallium from new scrap and GaAs wafer producer. Therefore, new concepts for a resource saving handling of gallium an...Assessment of element-specific recycling efficiency in WEEE pre-processing
Ueberschaar, Maximilian ; Geiping, Julia ; Zamzow, Malte ; Flamme, Sabine ; Rotter, Vera Susanne (2017)
Pre-processing is a crucial step to ensure the efficiency of subsequent processes and the quality of recyclates. The efficiency of pre-processing can be affected by high losses to undesignated output fractions. Standard batch tests usually provide mass balances and are a good proxy for bulk materials balances (iron/steel, aluminum, plastics). This article aims at harmonizing methodologies and ...Cellular injuries on spray‐dried Lactobacillus rhamnosus GG and its stability during food storage
Oluwaseun Sunny‐Roberts, Elizabeth ; Knorr, Dietrich (2011)
Purpose: This paper aims to evaluate the cellular injuries associated with spray‐drying of Lactobacillus rhamnosus GG (LGG) in trehalose/monosodium glutamate (MSG) media by means of flow cytometry measurements; and also whether, and to what extent, the probiotic remain stable and viable in food formulations. Design/methodology/approach: Spray‐drying was applied in the production of trehalose‐ba...A study on the thermal conversion of scheelite-type ABO(4) into perovskite-type AB(O,N)(3)
Li, Wenjie ; Li, Duan ; Gao, Xin ; Gurlo, Aleksander ; Zander, Stefan ; Jones, Philip ; Navrotsky, Alexandra ; Shen, Zhijian ; Riedel, Ralf ; Ionescu, Emanuel (2015)
Phase-pure scheelite AMoO(4) and AWO(4) (A = Ba, Sr, Ca) were thermally treated under an ammonia atmosphere at 400 to 900 degrees C. SrMoO4 and SrWO4 were shown to convert into cubic perovskite SrMoO2N and SrWO1.5N1.5, at 700 degrees C and 900 degrees C respectively, and to form metastable intermediate phases (scheelite SrMoO4-xNx and SrWO4-xNx), as revealed by X-ray diffraction (XRD), elementa...Slow crystallisation of a monodisperse foam stabilised against coarsening
Meagher, Aaron J. ; Whyte, David ; Banhart, John ; Hutzler, Stefan ; Weaire, Denis ; García-Moreno, Francisco (2015)
The evolution of a three-dimensional monodisperse foam was investigated using X-ray tomography over the course of seven days. The coarsening of the sample was inhibited through the use of perfluorohexane gas. The internal configuration of bubbles is seen to change markedly, evolving from a disordered arrangement towards a more ordered state. We chart this ordering process through the use of the...A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
Maschmeyer, Ilka ; Lorenz, Alexandra K. ; Schimek, Katharina ; Hasenberg, Tobias ; Ramme, Anja P. ; Hübner, Juliane ; Lindner, Marcus ; Drewell, Christopher ; Bauer, Sophie ; Thomas, Alexander ; Sambo, Naomia Sisoli ; Sonntag, Frank ; Lauster, Roland ; Marx, Uwe (2015)
Systemic absorption and metabolism of drugs in the small intestine, metabolism by the liver as well as excretion by the kidney are key determinants of efficacy and safety for therapeutic candidates. However, these systemic responses of applied substances lack in most in vitro assays. In this study, a microphysiological system maintaining the functionality of four organs over 28 days in co-cultu...Annihilation of structural defects in chalcogenide absorber films for high-efficiency solar cells
Mainz, Roland ; Sanli, Ekin Simsek ; Stange, Helena ; Azulay, Doron ; Brunken, Stephan ; Greiner, Dieter ; Hajaj, Shir ; Heinemann, Marc D. ; Kaufmann, Christian A. ; Klaus, Manuela ; Ramasse, Quentin M. ; Rodriguez-Alvarez, Humberto ; Weber, Alfons ; Balberg, Isaac ; Millo, Oded ; van Aken, Peter A. ; Abou-Ras, Daniel (2016)
In polycrystalline semiconductor absorbers for thin-film solar cells, structural defects may enhance electron-hole recombination and hence lower the resulting energy conversion efficiency. To be able to efficiently design and optimize fabrication processes that result in high-quality materials, knowledge of the nature of structural defects as well as their formation and annihilation during film...The contrasting effect of the Ta/Nb ratio in (111)-layered B-site deficient hexagonal perovskite Ba5Nb4-xTaxO15 crystals on visible-light-induced photocatalytic water oxidation activity of their oxynitride derivatives
Hojamberdiev, Mirabbos ; Bekheet, Maged F. ; Zahedi, Ehsan ; Wagata, Hajime ; Vequizo, Junie Jhon M. ; Yamakata, Akira ; Yubuta, Kunio ; Gurlo, Aleksander ; Domen, Kazunari ; Teshima, Katsuya (2016)
The effect of the Ta/Nb ratio in the (111)-layered B-site deficient hexagonal perovskite Ba5Nb4-xTaxO15 (0 <= x <= 4) crystals grown by a KCl flux method on visible-light-induced photocatalytic water oxidation activity of their oxynitride derivatives BaNb1-xTaxO2N (0 <= x <= 1) was investigated. The Rietveld refinement of X-ray data revealed that all Ba5Nb4-xTaxO15 samples were well crystallize...Toward microbioreactor arrays
Glauche, Florian ; John, Gernot T. ; Arain, Sarina ; Knepper, Andreas ; Neubauer, Antje ; Goelling, Detlef ; Lang, Christine ; Violet, Norman ; King, Rudibert ; Neubauer, Peter (2015)
In this study, a slow-responding chemo-optical sensor for dissolved oxygen (DO) integrated into a 96-well plate was developed. The slow response time ensures that the measured oxygen value does not change much during plate transport to the microplate reader. The sensor therefore permits at-line DO measurement of microbial cultures. Moreover, it eliminates the necessity of individual optical mea...Characterization and mechanical properties investigation of the cellulose/gypsum composite
Nindiyasari, Fitriana ; Griesshaber, Erika ; Zimmermann, Tanja ; Manian, Avinash Pradip ; Randow, Clemens ; Zehbe, Rolf ; Fernandez-Diaz, Lurdes ; Ziegler, Andreas ; Fleck, Claudia ; Schmahl, Wolfgang W. (2016)
We synthesized cellulose/gypsum composites in the presence and absence of sodium alginate and investigated the interaction between the composite components as well as the mechanical properties of the final composites. Four different types of cellulose fiber materials were used: cellulose UFC100, cellulose B400, nanofibrillated cellulose, and Lyocell fiber. For all investigated composites the to...Southern promises: a snapshot of the microbiology research landscape in South America based on bibliometric data
Nai, Corrado (2017-09)
Scientists have a single currency for productivity and impact: published articles. In an effort to map the global research landscape in microbiology, and to obviate the current lack of bibliometric analysis in the field, FEMS—the Federation of European Microbiological Societies—generated a dataset encompassing an exhaustive, worldwide list of microbiology studies for 2013–14, which further incl...Ex vivo Charakterisierung von humanen Autoantigen-spezifischen CD4+ T-Zellen mit Fokus auf Multiple Sklerose
Gamradt, Stefanie (2017)
Trotz intensiver Forschung ist unklar, ob Myelin-reaktive CD4+ T-Zellen in der Pathogenese der Multiplen Sklerose (MS) eine relevante Rolle spielen. Ein Grund dafür ist das Fehlen einer Methode für ihre direkte Analyse. In dieser Arbeit ist es mit Hilfe der magnetischen Anreicherung von spezifisch-aktivierten CD154+ konventionellen und CD137+ regulato-rischen T-Zellen in Kombination mit multipa...CE_Method. A MATLAB function for calculating the part load behaviour of absorption chillers and heat pumps based on (C)haracteristic (E)quations
Albers, Jan (2017-09-26)
The algorithm CE_METHOD calculates the part load behaviour of single stage absorption chillers and heat pumps explicitly as function of inlet temperatures and flow rates. For the characterisation of the chiller or heat pump the heat transfer capabilities (i.e. the UA-values) of five heat exchangers (Desorber, Evaporator, Condenser, Absorber and Solution heat exchanger) have to be known.Anaerobic transformation of brominated aromatic compounds by Dehalococcoides mccartyi strain CBDB1
Yang, Chao (2017)
Brominated flame retardants are widely used compounds for fire safety in our daily life. Many of them have been reported to be toxic to humans and identified as environmental contaminants. Dehalococcoides mccartyi strains are well known for their dependence on organohalide respiration as an energy conserving process and have therefore been intensively studied. So far, much less investigations w...Interfacial properties of saponins from Quillaja saponaria Molina and their functionality in dispersed systems
Böttcher, Sandra (2017)
The aim of the present thesis was to connect interfacial properties of saponins at aqueous interfaces with their behavior in dispersed systems. Thereby the influence of changes in pH and ionic strength and interactions with β-lactoglobulin were discussed using spectroscopic equipment and knowledge on molecular structure. Saponins are phytochemicals that can be found in numerous plant species i...
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