Bouvier, Guy ; Higgins, David ; Spolidoro, Maria ; Carrel, Damien ; Mathieu, Benjamin ; Léna, Clément ; Dieudonné, Stéphane ; Barbour, Boris ; Brunel, Nicolas ; Casado, Mariano (2016-03-24)
Numerous studies have shown that cerebellar function is related to the plasticity at the synapses between parallel fibers and Purkinje cells. How specific input patterns determine plasticity outcomes, as well as the biophysics underlying plasticity of these synapses, remain unclear. Here, we characterize the patterns of activity that lead to postsynaptically expressed LTP using both in vivo and...Functional consequences of inhibitory plasticity: homeostasis, the excitation-inhibition balance and beyond
Sprekeler, Henning (2017-05-10)
Computational neuroscience has a long-standing tradition of investigating the consequences of excitatory synaptic plasticity. In contrast, the functions of inhibitory plasticity are still largely nebulous, particularly given the bewildering diversity of interneurons in the brain. Here, we review recent computational advances that provide first suggestions for the functional roles of inhibitory ...Linking appearance to neural activity through the study of the perception of lightness in naturalistic contexts
Maertens, Marianne ; Shapley, Robert (2013)
The present paper deals with the classical question how a psychological experience, in this case apparent lightness, is linked by intervening neural processing to physical variables. We address two methodological issues: (a) how does one know the appropriate physical variable (what is the right x ?) to look at, and (b) how can behavioral measurements be used to probe the internal transformation...Exploitation of environmental constraints in human and robotic grasping
Eppner, Clemens ; Deimel, Raphael ; Álvarez-Ruiz, José ; Maertens, Marianne ; Brock, Oliver (2015)
We investigate the premise that robust grasping performance is enabled by exploiting constraints present in the environment. These constraints, leveraged through motion in contact, counteract uncertainty in state variables relevant to grasp success. Given this premise, grasping becomes a process of successive exploitation of environmental constraints, until a successful grasp has been establish...