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Main Title: Recent advances in modeling and analysis of bioelectric and biomagnetic sources
Author(s): Sander, Tilmann H.
Knösche, Thomas R.
Schlögl, Alois
Kohl, Florian
Wolters, Carsten H.
Haueisen, Jens
Trahms, Lutz
Type: Article
Language Code: en
Abstract: Determining the centers of electrical activity in the human body and the connectivity between different centers of activity in the brain is an active area of research. To understand brain function and the nature of cardiovascular diseases requires sophisticated methods applicable to non-invasively measured bioelectric and biomagnetic data. As it is difficult to solve for all unknown parameters at once, several strains of data analysis have been developed, each trying to solve a different part of the problem and each requiring a different set of assumptions. Current trends and results from major topics of electro- and magnetoencephalographic data analysis are presented here together with the aim of stimulating research into the unification of the different approaches. The following topics are discussed: source reconstruction using detailed finite element modeling to locate sources deep in the brain; connectivity analysis for the quantification of strength and direction of information flow between activity centers, preferably incorporating an inverse solution; the conflict between the statistical independence assumption of sources and a possible connectivity; the verification and validation of results derived from non-invasively measured data through animal studies and phantom measurements. This list already indicates the benefits of a unified view.
Issue Date: 2010
Date Available: 29-Nov-2017
DDC Class: 610 Medizin und Gesundheit
Subject(s): autoregressive modeling
finite element method
inverse problem
statistical independence
Journal Title: Biomedical engineering = Biomedizinische Technik
Publisher: De Gruyter
Publisher Place: Berlin [u.a.]
Volume: 55
Issue: 2
Publisher DOI: 10.1515/bmt.2010.027
Page Start: 65
Page End: 76
EISSN: 0013-5585
ISSN: 1862-278X
Notes: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
Appears in Collections:FG Elektronik und medizinische Signalverarbeitung » Publications

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