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Main Title: Functional consequences of inhibitory plasticity: homeostasis, the excitation-inhibition balance and beyond
Author(s): Sprekeler, Henning
Type: Article
Language Code: en
Abstract: Computational neuroscience has a long-standing tradition of investigating the consequences of excitatory synaptic plasticity. In contrast, the functions of inhibitory plasticity are still largely nebulous, particularly given the bewildering diversity of interneurons in the brain. Here, we review recent computational advances that provide first suggestions for the functional roles of inhibitory plasticity, such as a maintenance of the excitation-inhibition balance, a stabilization of recurrent network dynamics and a decorrelation of sensory responses. The field is still in its infancy, but given the existing body of theory for excitatory plasticity, it is likely to mature quickly and deliver important insights into the self-organization of inhibitory circuits in the brain.
Issue Date: 10-May-2017
Date Available: 28-May-2018
DDC Class: 570 Biowissenschaften; Biologie
610 Medizin und Gesundheit
Subject(s): excitatory plasticity
excitation-inhibition balance
inhibitory plasticity
Journal Title: Current opinion in neurobiology : reviews of all advances ; evaluation of key references ; comprehensive listing of papers
Publisher: Elsevier
Publisher Place: Oxford
Volume: 43
Publisher DOI: 10.1016/j.conb.2017.03.014
Page Start: 198
Page End: 203
ISSN: 0959-4388
Appears in Collections:FG Modellierung kognitiver Prozesse » Publications

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