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Main Title: Naphthoquinone Derivatives and Lignans from the Paraguayan Crude Drug “Tayï Pytá” (Tabebuia heptaphylla, Bignoniaceae)
Author(s): Schmeda-Hirschmann, Guillermo
Papastergiou, Fani
Type: Article
Language Code: en
Abstract: The Paraguayan crude drug “tayï pytá” is used to treat cancer, wounds and inflammation. It consist of the bark and trunkwood of Tabebuia heptaphylla (Bignoniaceae). A phytochemical study of the crude drug gave, in addition to previously described naphthoquinones and the known lignans cycloolivil and secoisolariciresinol, three new lapachenol (lapachonone)-, two naphthofuran-, a chromone and a naphthalene derivative. The structures were elucidated by means of high field NMR spectroscopy. The biological activity of the main compound lapachol and the related α-lapachone as well as the lignans cycloolivil and secoisolariciresinol can explain, at least in part, the effect atributed to the crude drug in Paraguayan folk medicine.
Issue Date: 2003
Date Available: 2-Oct-2018
DDC Class: 570 Biowissenschaften; Biologie
Subject(s): Tabebuia heptaphylla
Journal Title: Zeitschrift für Naturforschung C
Publisher: De Gruyter
Publisher Place: Berlin
Volume: 58
Issue: 7-8
Publisher DOI: 10.1515/znc-2003-7-809
Page Start: 495
Page End: 501
EISSN: 1865-7125
ISSN: 0939-5075
Appears in Collections:Inst. Chemie » Publications

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