3D Free‐breathing multichannel absolute B1+ Mapping in the human body at 7T

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dc.contributor.authorDietrich, Sebastian
dc.contributor.authorAigner, Christoph S.
dc.contributor.authorKolbitsch, Christoph
dc.contributor.authorMayer, Johannes
dc.contributor.authorLudwig, Juliane
dc.contributor.authorSchmidt, Simon
dc.contributor.authorSchaeffter, Tobias
dc.contributor.authorSchmitter, Sebastian
dc.date.accessioned2021-02-17T11:57:58Z
dc.date.available2021-02-17T11:57:58Z
dc.date.issued2020-12-07
dc.date.updated2021-02-15T10:12:53Z
dc.description.abstractPurpose To introduce and investigate a method for free‐breathing three‐dimensional (3D) B1+ mapping of the human body at ultrahigh field (UHF), which can be used to generate homogenous flip angle (FA) distributions in the human body at UHF. Methods A 3D relative B1+ mapping sequence with a radial phase‐encoding (RPE) k‐space trajectory was developed and applied in 11 healthy subjects at 7T. An RPE‐based actual flip angle mapping method was applied with a dedicated B1+ shim setting to calibrate the relative B1+ maps yielding absolute B1+ maps of the individual transmit channels. The method was evaluated in a motion phantom and by multidimensional in vivo measurements. Additionally, 3D gradient echo scans with and without static phase‐only B1+ shims were used to qualitatively validate B1+ shim predictions. Results The phantom validation revealed good agreement for B1+ maps between dynamic measurement and static reference acquisition. The proposed 3D method was successfully validated in vivo by comparing magnitude and phase distributions with a 2D Cartesian reference. 3D B1+ maps free from visible motion artifacts were successfully acquired for 11 subjects with body mass indexes ranging from 19 kg/m2 to 34 kg/m2. 3D respiration‐resolved absolute B1+ maps indicated FA differences between inhalation and exhalation up to 15% for one channel and up to 24% for combined channels for shallow breathing. Conclusion The proposed method provides respiration‐resolved absolute 3D B1+ maps of the human body at UHF, which enables the investigation and development of 3D B1+ shimming and parallel transmission methods to further enhance body imaging at UHF.en
dc.identifier.eissn1522-2594
dc.identifier.issn0740-3194
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/12618
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-11427
dc.language.isoenen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subject.ddc610 Medizin und Gesundheitde
dc.subject.other7 Teslaen
dc.subject.otheractual flip angle imagingen
dc.subject.otherbody imagingen
dc.subject.otherB1+ mappingen
dc.subject.otherradial phase encodingen
dc.subject.otherultrahigh fielden
dc.title3D Free‐breathing multichannel absolute B1+ Mapping in the human body at 7Ten
dc.typeArticleen
dc.type.versionpublishedVersionen
dcterms.bibliographicCitation.doi10.1002/mrm.28602en
dcterms.bibliographicCitation.issue5en
dcterms.bibliographicCitation.journaltitleMagnetic Resonance in Medicineen
dcterms.bibliographicCitation.originalpublishernameWileyen
dcterms.bibliographicCitation.originalpublisherplaceNew York, NYen
dcterms.bibliographicCitation.pageend2567en
dcterms.bibliographicCitation.pagestart2552en
dcterms.bibliographicCitation.volume85en
tub.accessrights.dnbfreeen
tub.affiliationFak. 5 Verkehrs- und Maschinensysteme::Inst. Maschinenkonstruktion und Systemtechnik::FG Medizintechnikde
tub.affiliation.facultyFak. 5 Verkehrs- und Maschinensystemede
tub.affiliation.groupFG Medizintechnikde
tub.affiliation.instituteInst. Maschinenkonstruktion und Systemtechnikde
tub.publisher.universityorinstitutionTechnische Universität Berlinen

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