Wearable Cardiorespiratory Monitoring Employing a Multimodal Digital Patch Stethoscope: Estimation of ECG, PEP, LVET and Respiration Using a 55 mm Single-Lead ECG and Phonocardiogram

dc.contributor.authorKlum, Michael
dc.contributor.authorUrban, Mike
dc.contributor.authorTigges, Timo
dc.contributor.authorPielmus, Alexandru-Gabriel
dc.contributor.authorFeldheiser, Aarne
dc.contributor.authorSchmitt, Theresa
dc.contributor.authorOrglmeister, Reinhold
dc.date.accessioned2020-06-11T16:10:19Z
dc.date.available2020-06-11T16:10:19Z
dc.date.issued2020-04-04
dc.date.updated2020-05-05T14:55:39Z
dc.description.abstractCardiovascular diseases are the main cause of death worldwide, with sleep disordered breathing being a further aggravating factor. Respiratory illnesses are the third leading cause of death amongst the noncommunicable diseases. The current COVID-19 pandemic, however, also highlights the impact of communicable respiratory syndromes. In the clinical routine, prolonged postanesthetic respiratory instability worsens the patient outcome. Even though early and continuous, long-term cardiorespiratory monitoring has been proposed or even proven to be beneficial in several situations, implementations thereof are sparse. We employed our recently presented, multimodal patch stethoscope to estimate Einthoven electrocardiogram (ECG) Lead I and II from a single 55 mm ECG lead. Using the stethoscope and ECG subsystems, the pre-ejection period (PEP) and left ventricular ejection time (LVET) were estimated. ECG-derived respiration techniques were used in conjunction with a novel, phonocardiogram-derived respiration approach to extract respiratory parameters. Medical-grade references were the SOMNOmedics SOMNO HDTM and Osypka ICON-CoreTM. In a study including 10 healthy subjects, we analyzed the performances in the supine, lateral, and prone position. Einthoven I and II estimations yielded correlations exceeding 0.97. LVET and PEP estimation errors were 10% and 21%, respectively. Respiratory rates were estimated with mean absolute errors below 1.2 bpm, and the respiratory signal yielded a correlation of 0.66. We conclude that the estimation of ECG, PEP, LVET, and respiratory parameters is feasible using a wearable, multimodal acquisition device and encourage further research in multimodal signal fusion for respiratory signal estimation.en
dc.description.sponsorshipDFG, 414044773, Open Access Publizieren 2019 - 2020 / Technische Universität Berlinen
dc.identifier.eissn1424-8220
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/11327
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-10213
dc.language.isoenen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subject.ddc610 Medizin und Gesundheitde
dc.subject.ddc004 Datenverarbeitung; Informatikde
dc.subject.otherECGen
dc.subject.otherPEPen
dc.subject.otherLVETen
dc.subject.otherrespiration rateen
dc.subject.otherwearable cardiorespiratory monitoringen
dc.subject.otherpatchen
dc.subject.otherdigital stethoscopeen
dc.subject.otherECG-derived respirationen
dc.subject.otherphonocardiogram-derived respirationen
dc.subject.otherneural networken
dc.titleWearable Cardiorespiratory Monitoring Employing a Multimodal Digital Patch Stethoscope: Estimation of ECG, PEP, LVET and Respiration Using a 55 mm Single-Lead ECG and Phonocardiogramen
dc.typeArticleen
dc.type.versionpublishedVersionen
dcterms.bibliographicCitation.articlenumber2033en
dcterms.bibliographicCitation.doi10.3390/s20072033en
dcterms.bibliographicCitation.issue7en
dcterms.bibliographicCitation.journaltitleSensorsen
dcterms.bibliographicCitation.originalpublishernameMDPIen
dcterms.bibliographicCitation.originalpublisherplaceBaselen
dcterms.bibliographicCitation.volume20en
tub.accessrights.dnbfreeen
tub.affiliationFak. 4 Elektrotechnik und Informatik::Inst. Energie- und Automatisierungstechnik::FG Elektronik und medizinische Signalverarbeitungde
tub.affiliation.facultyFak. 4 Elektrotechnik und Informatikde
tub.affiliation.groupFG Elektronik und medizinische Signalverarbeitungde
tub.affiliation.instituteInst. Energie- und Automatisierungstechnikde
tub.publisher.universityorinstitutionTechnische Universität Berlinen

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