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Surface enhanced vibrational spectroscopic evidence for an alternative DNA-independent redox activation of endonuclease III

Moe, Elin; Sezer, Murat; Hildebrandt, Peter; Todorovic, Smilja

Surface enhanced vibrational spectro-electrochemistry of endonuclease III provides direct evidence that the [4Fe-4S] cluster is responsible for the enzyme redox activity, and that this process is not exclusively DNA-mediated, as currently proposed. We report the first surface enhanced resonance Raman spectrum of a [4Fe-4S](2+) cluster containing enzyme.
Published in: Chemical communications, 10.1039/c4cc09498k, Royal Society of Chemistry
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