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In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues
In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues
Matthes, Diana; Richter, Lennart; Müller, Jane; Denisiuk, Alexander; Feifel, Sven C.; Xu, Yuquan; Espinosa-Artiles, Patricia; Süßmuth, Roderich D.; Molnár, István
Inst. Chemie
New beauvericins have been synthesized using the nonribosomal peptide synthetase BbBEAS from the entomopathogenic fungus Beauveria bassiana. Chemical diversity was generated by in vitro chemoenzymatic and in vivo whole cell biocatalytic syntheses using either a B. bassiana mutant or an E. coli strain expressing the bbBeas gene.
- Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
- This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
