Self-assembled single-stranded DNA nano-networks in solution and at surfaces

dc.contributor.authorSimon, Miriam
dc.contributor.authorPrause, Albert
dc.contributor.authorPrause, Albert
dc.contributor.authorGradzielski, Michael
dc.date.accessioned2022-09-09T13:37:26Z
dc.date.available2022-09-09T13:37:26Z
dc.date.issued2022-02-17
dc.description.abstractWe studied the directed self-assembly of two types of complementary single-stranded DNA (ssDNA) strands [i.e., poly(dA) and poly(dT)] into more complex, organized, and percolating networks in dilute solutions and at surfaces. Understanding ssDNA self-assembly into 2D networks on surfaces is important for the use of such networks in the fabrication of well-defined nanotechnological devices, as, for instance, required in nanoelectronics or for biosensing. To control the formation of 2D networks on surfaces, it is important to know whether DNA assemblies are formed already in dilute solutions or only during the drying/immobilization process at the surface, where the concentration automatically increases. Fluorescence cross-correlation spectroscopy clearly shows the presence of larger DNA complexes in mixed poly(dA) and poly(dT) solutions already at very low DNA concentrations (<1 nM), that is, well below the overlap concentration. Here, we describe for the first time such supramolecular complexes in solution and how their structure depends on the ssDNA length and concentration and ionic strength. Hence, future attempts to control such networks should also focus on network precursors in solution and not only on their immobilization on surfaces.en
dc.identifier.eissn1526-4602
dc.identifier.issn1525-7797
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/17405
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-16186
dc.language.isoenen
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.ddc540 Chemie und zugeordnete Wissenschaftende
dc.subject.otherssDNAen
dc.subject.otherassemblyen
dc.subject.otherfluorescence cross-correlation spectroscopyen
dc.subject.othernetworksen
dc.subject.otherbionanotechnologyen
dc.titleSelf-assembled single-stranded DNA nano-networks in solution and at surfacesen
dc.typeArticleen
dc.type.versionacceptedVersionen
dcterms.bibliographicCitation.doi10.1021/acs.biomac.1c01493en
dcterms.bibliographicCitation.issue3en
dcterms.bibliographicCitation.journaltitleBiomacromoleculesen
dcterms.bibliographicCitation.originalpublishernameAmerican Chemical Societyen
dcterms.bibliographicCitation.originalpublisherplaceWashington, DCen
dcterms.bibliographicCitation.pageend1250en
dcterms.bibliographicCitation.pagestart1242en
dcterms.bibliographicCitation.volume23en
tub.accessrights.dnbdomain*
tub.affiliationFak. 2 Mathematik und Naturwissenschaften::Inst. Chemie::FG Physikalische Chemie / Molekulare Materialwissenschaftende
tub.affiliation.facultyFak. 2 Mathematik und Naturwissenschaftende
tub.affiliation.groupFG Physikalische Chemie / Molekulare Materialwissenschaftende
tub.affiliation.instituteInst. Chemiede
tub.publisher.universityorinstitutionTechnische Universität Berlinen

Files

Original bundle
Now showing 1 - 2 of 2
Loading…
Thumbnail Image
Name:
Simon_etal_Self-Assembled_2022.pdf
Size:
1.26 MB
Format:
Adobe Portable Document Format
Description:
Loading…
Thumbnail Image
Name:
Simon_etal_Self-Assembled_2022_SupportingInformation.pdf
Size:
2.1 MB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
4.86 KB
Format:
Item-specific license agreed upon to submission
Description:

Collections