Thermal segment microwell plate control for automated liquid handling setups

dc.contributor.authorSeidel, Simon
dc.contributor.authorWinkler, Katja F.
dc.contributor.authorKurreck, Anke
dc.contributor.authorCruz-Bournazou, Mariano Nicolas
dc.contributor.authorPaulick, Katharina
dc.contributor.authorGroß, Sebastian
dc.contributor.authorNeubauer, Peter
dc.date.accessioned2024-04-24T12:43:47Z
dc.date.available2024-04-24T12:43:47Z
dc.date.issued2024-02-21
dc.description.abstractAutomated high-throughput liquid handling operations in biolabs necessitate miniaturised and automatised equipment for effective space utilisation and system integration. This paper presents a thermal segment microwell plate control unit designed for enhanced microwell-based experimentation in liquid handling setups. The development of this device stems from the need to move towards geometry standardization and system integration of automated lab equipment. It incorporates features based on Smart Sensor and Sensor 4.0 concepts. An enzymatic activity assay is implemented with the developed device on a liquid handling station, allowing fast characterisation via a high-throughput approach. The device outperforms other comparable devices in certain metrics based on automated liquid handling requirements and addresses the needs of future biolabs in automation, especially in high-throughput screening.en
dc.description.sponsorshipTU Berlin, Open-Access-Mittel – 2024
dc.identifier.eissn1473-0189
dc.identifier.issn1473-0197
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/21581
dc.identifier.urihttps://doi.org/10.14279/depositonce-20381
dc.language.isoen
dc.publisherRoyal Society of Chemistry (RSC)
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.subject.ddc500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften
dc.subject.otherliquid handlingen
dc.subject.otherbiolabsen
dc.subject.othereffective space utilisationen
dc.subject.othersystem integrationen
dc.subject.othermicrowell plateen
dc.titleThermal segment microwell plate control for automated liquid handling setups
dc.typeArticle
dc.type.versionpublishedVersion
dcterms.bibliographicCitation.doi10.1039/d3lc00714f
dcterms.bibliographicCitation.issue8
dcterms.bibliographicCitation.journaltitleLab on a Chip
dcterms.bibliographicCitation.originalpublishernameRoyal Society of Chemistry
dcterms.bibliographicCitation.originalpublisherplaceCambridge
dcterms.bibliographicCitation.pageend2236
dcterms.bibliographicCitation.pagestart2224
dcterms.bibliographicCitation.volume24
dcterms.rightsHolder.referenceCreative-Commons-Lizenz
tub.accessrights.dnbfree
tub.affiliationFak. 3 Prozesswissenschaften::Inst. Biotechnologie::FG Bioverfahrenstechnik
tub.publisher.universityorinstitutionTechnische Universität Berlin

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