Beyond Carbon: Enantioselective and Enantiospecific Reactions with Catalytically Generated Boryl- and Silylcopper Intermediates

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dc.contributor.authorXue, Weichao
dc.contributor.authorOestreich, Martin
dc.date.accessioned2021-12-27T12:22:55Z
dc.date.available2021-12-27T12:22:55Z
dc.date.issued2020-07-09
dc.description.abstractCatalytic asymmetric C-C bond formation with alkylcopper intermediates as carbon nucleophiles is now textbook chemistry. Related chemistry with boron and silicon nucleophiles where the boryl- and accordingly silylcopper intermediates are catalytically regenerated from bench-stable pronucleophiles had been underdeveloped for years or did not even exist until recently. Over the past decade, asymmetric copper catalysis employing those main-group elements as nucleophiles rapidly transformed into a huge field in its own right with an impressive breadth of enantioselective C-B and C-Si bond-forming reactions, respectively. Its current state of the art does not have to shy away from comparison with that of boron's and silicon's common neighbor in the periodic table, carbon. This Outlook is not meant to be a detailed summary of those manifold advances. It rather aims at providing a brief conceptual summary of what forms the basis of the latest exciting progress, especially in the area of three-component reactions and cross-coupling reactions.en
dc.identifier.eissn2374-7951
dc.identifier.issn2374-7943
dc.identifier.pmid32724842
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/16009
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-14783
dc.language.isoenen
dc.rights.urihttps://pubs.acs.org/page/policy/authorchoice_termsofuse.htmlen
dc.subject.ddc540 Chemie und zugeordnete Wissenschaftende
dc.subject.otherhydrocarbonsen
dc.subject.otheraddition reactionsen
dc.subject.othersubstitution reactionsen
dc.subject.otherelectrophilesen
dc.subject.othersiliconen
dc.titleBeyond Carbon: Enantioselective and Enantiospecific Reactions with Catalytically Generated Boryl- and Silylcopper Intermediatesen
dc.typeArticleen
dc.type.versionpublishedVersionen
dcterms.bibliographicCitation.doi10.1021/acscentsci.0c00738en
dcterms.bibliographicCitation.issue7en
dcterms.bibliographicCitation.journaltitleACS Central Scienceen
dcterms.bibliographicCitation.originalpublishernameAmerican Chemical Society (ACS)en
dcterms.bibliographicCitation.originalpublisherplaceWashingtonen
dcterms.bibliographicCitation.pageend1081en
dcterms.bibliographicCitation.pagestart1070en
dcterms.bibliographicCitation.volume6en
tub.accessrights.dnbfreeen
tub.affiliationFak. 2 Mathematik und Naturwissenschaften::Inst. Chemie::FG Organische Chemie / Synthese und Katalysede
tub.affiliation.facultyFak. 2 Mathematik und Naturwissenschaftende
tub.affiliation.groupFG Organische Chemie / Synthese und Katalysede
tub.affiliation.instituteInst. Chemiede
tub.publisher.universityorinstitutionTechnische Universität Berlinen

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