Design and Fabrication of a BiCMOS Dielectric Sensor for Viscosity Measurements: A Possible Solution for Early Detection of COPD
| dc.contributor.author | Soltani Zarrin, Pouya | |
| dc.contributor.author | Jamal, Farabi Ibne | |
| dc.contributor.author | Guha, Subhajit | |
| dc.contributor.author | Wessel, Jan | |
| dc.contributor.author | Kissinger, Dietmar | |
| dc.contributor.author | Wenger, Christian | |
| dc.date.accessioned | 2019-09-11T16:17:34Z | |
| dc.date.available | 2019-09-11T16:17:34Z | |
| dc.date.issued | 2018-08-21 | |
| dc.date.updated | 2019-08-01T02:46:09Z | |
| dc.description.abstract | The viscosity variation of sputum is a common symptom of the progression of Chronic Obstructive Pulmonary Disease (COPD). Since the hydration of the sputum defines its viscosity level, dielectric sensors could be used for the characterization of sputum samples collected from patients for early diagnosis of COPD. In this work, a CMOS-based dielectric sensor for the real-time monitoring of sputum viscosity was designed and fabricated. A proper packaging for the ESD-protection and short-circuit prevention of the sensor was developed. The performance evaluation results show that the radio frequency sensor is capable of measuring dielectric constant of biofluids with an accuracy of 4.17%. Integration of this sensor into a portable system will result in a hand-held device capable of measuring viscosity of sputum samples of COPD-patients for diagnostic purposes. | en |
| dc.description.sponsorship | BMBF, 13N13862, POC-Sensorplattform für chronisch-entzündliche Atemwegserkrankungen (EXASENS) - On-Chip-CMOS-Sensorik | en |
| dc.identifier.eissn | 2079-6374 | |
| dc.identifier.uri | https://depositonce.tu-berlin.de/handle/11303/10004 | |
| dc.identifier.uri | http://dx.doi.org/10.14279/depositonce-8995 | |
| dc.language.iso | en | en |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en |
| dc.subject.ddc | 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten | de |
| dc.subject.other | Sputum–Mucin | en |
| dc.subject.other | dielectric measurements | en |
| dc.subject.other | CMOS viscosity sensor | en |
| dc.subject.other | radio frequency sensor | en |
| dc.subject.other | Viscometer | en |
| dc.subject.other | biosensors | en |
| dc.subject.other | precision diagnostics | en |
| dc.title | Design and Fabrication of a BiCMOS Dielectric Sensor for Viscosity Measurements: A Possible Solution for Early Detection of COPD | en |
| dc.type | Article | en |
| dc.type.version | publishedVersion | en |
| dcterms.bibliographicCitation.articlenumber | 78 | en |
| dcterms.bibliographicCitation.doi | 10.3390/bios8030078 | en |
| dcterms.bibliographicCitation.issue | 3 | en |
| dcterms.bibliographicCitation.journaltitle | Biosensors | en |
| dcterms.bibliographicCitation.originalpublishername | MDPI | en |
| dcterms.bibliographicCitation.originalpublisherplace | Basel | en |
| dcterms.bibliographicCitation.volume | 8 | en |
| tub.accessrights.dnb | free | en |
| tub.affiliation | Fak. 4 Elektrotechnik und Informatik::Inst. Hochfrequenz- und Halbleiter-Systemtechnologien | de |
| tub.affiliation.faculty | Fak. 4 Elektrotechnik und Informatik | de |
| tub.affiliation.institute | Inst. Hochfrequenz- und Halbleiter-Systemtechnologien | de |
| tub.publisher.universityorinstitution | Technische Universität Berlin | en |