Hydrodynamics and Mass Transfer Analysis in BioFlow® Bioreactor Systems

dc.contributor.authorKordas, Marian
dc.contributor.authorKonopacki, Maciej
dc.contributor.authorGrygorcewicz, Bartłomiej
dc.contributor.authorAugustyniak, Adrian
dc.contributor.authorMusik, Daniel
dc.contributor.authorWójcik, Krzysztof
dc.contributor.authorJędrzejczak-Silicka, Magdalena
dc.contributor.authorRakoczy, Rafał
dc.date.accessioned2020-11-13T12:15:30Z
dc.date.available2020-11-13T12:15:30Z
dc.date.issued2020-10-19
dc.date.updated2020-11-11T19:49:38Z
dc.description.abstractBiotechnological processes involving the presence of microorganisms are realized by using various types of stirred tanks or laboratory-scale dual-impeller commercial bioreactor. Hydrodynamics and mass transfer rate are crucial parameters describing the functionality and efficiency of bioreactors. Both parameters strictly depend on mixing applied during bioprocesses conducted in bioreactors. Establishing optimum hydrodynamics conditions for the realized process with microorganisms maximizes the yield of desired products. Therefore, our main objective was to analyze and define the main operational hydrodynamic parameters (including flow field, power consumption, mixing time, and mixing energy) and mass transfer process (in this case, gas–liquid transfer) of two different commercial bioreactors (BioFlo® 115 and BioFlo® 415). The obtained results are allowed using mathematical relationships to describe the analyzed processes that can be used to predict the mixing process and mass transfer ratio in BioFlo® bioreactors. The proposed correlations may be applied for the design of a scaled-up or scaled-down bioreactors.en
dc.identifier.eissn2227-9717
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/11936
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-10827
dc.language.isoenen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subject.ddc570 Biowissenschaften; Biologiede
dc.subject.otheragitationen
dc.subject.otherbioreactorsen
dc.subject.othermixingen
dc.subject.othermass transferen
dc.subject.othermodellingen
dc.subject.otherpower consumptionen
dc.titleHydrodynamics and Mass Transfer Analysis in BioFlow® Bioreactor Systemsen
dc.typeArticleen
dc.type.versionpublishedVersionen
dcterms.bibliographicCitation.articlenumber1311en
dcterms.bibliographicCitation.doi10.3390/pr8101311en
dcterms.bibliographicCitation.issue10en
dcterms.bibliographicCitation.journaltitleProcessesen
dcterms.bibliographicCitation.originalpublishernameMDPIen
dcterms.bibliographicCitation.originalpublisherplaceBaselen
dcterms.bibliographicCitation.volume8en
tub.accessrights.dnbfreeen
tub.affiliationFak. 6 Planen Bauen Umwelt::Inst. Bauingenieurwesen::FG Baustoffe und Bauchemiede
tub.affiliation.facultyFak. 6 Planen Bauen Umweltde
tub.affiliation.groupFG Baustoffe und Bauchemiede
tub.affiliation.instituteInst. Bauingenieurwesende
tub.publisher.universityorinstitutionTechnische Universität Berlinen

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