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Using alcohols as simple H2-equivalents for copper-catalysed transfer semihydrogenations of alkynes

Kaicharla, Trinadh; Zimmermann, Birte M.; Oestreich, Martin; Teichert, Johannes F.

Copper(I)/N-heterocyclic carbene complexes enable a transfer semihydrogenation of alkynes employing simple and readily available alcohols such as isopropanol. The practical overall protocol circumvents the use of commonly employed high pressure equipment when using dihydrogen (H2) on the one hand, and avoids the generation of stoichiometric silicon-based waste on the other hand, when hydrosilanes are used as terminal reductants.
Published in: Chemical Communications, 10.1039/C9CC06637C, Royal Society of Chemistry