Naphthoquinone Derivatives and Lignans from the Paraguayan Crude Drug “Tayï Pytá” (Tabebuia heptaphylla, Bignoniaceae)

dc.contributor.authorSchmeda-Hirschmann, Guillermo
dc.contributor.authorPapastergiou, Fani
dc.date.accessioned2018-10-02T14:02:02Z
dc.date.available2018-10-02T14:02:02Z
dc.date.issued2003
dc.description.abstractThe Paraguayan crude drug “tayï pytá” is used to treat cancer, wounds and inflammation. It consist of the bark and trunkwood of Tabebuia heptaphylla (Bignoniaceae). A phytochemical study of the crude drug gave, in addition to previously described naphthoquinones and the known lignans cycloolivil and secoisolariciresinol, three new lapachenol (lapachonone)-, two naphthofuran-, a chromone and a naphthalene derivative. The structures were elucidated by means of high field NMR spectroscopy. The biological activity of the main compound lapachol and the related α-lapachone as well as the lignans cycloolivil and secoisolariciresinol can explain, at least in part, the effect atributed to the crude drug in Paraguayan folk medicine.en
dc.identifier.eissn1865-7125
dc.identifier.issn0939-5075
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/8265
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-7416
dc.language.isoen
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject.ddc570 Biowissenschaften; Biologiede
dc.subject.otherTabebuia heptaphyllaen
dc.subject.otherBignoniaceaeen
dc.subject.otherNaphthoquinonesen
dc.titleNaphthoquinone Derivatives and Lignans from the Paraguayan Crude Drug “Tayï Pytá” (Tabebuia heptaphylla, Bignoniaceae)en
dc.typeArticleen
dc.type.versionpublishedVersionen
dcterms.bibliographicCitation.doi10.1515/znc-2003-7-809
dcterms.bibliographicCitation.issue7-8
dcterms.bibliographicCitation.journaltitleZeitschrift für Naturforschung Cde
dcterms.bibliographicCitation.originalpublishernameDe Gruyteren
dcterms.bibliographicCitation.originalpublisherplaceBerlinen
dcterms.bibliographicCitation.pageend501
dcterms.bibliographicCitation.pagestart495
dcterms.bibliographicCitation.volume58
tub.accessrights.dnbfree
tub.affiliationFak. 2 Mathematik und Naturwissenschaften::Inst. Chemiede
tub.affiliation.facultyFak. 2 Mathematik und Naturwissenschaftende
tub.affiliation.instituteInst. Chemiede
tub.publisher.universityorinstitutionTechnische Universität Berlinde

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