Low-quality animal by-product streams for the production of PHA-biopolymers: fats, fat/protein-emulsions and materials with high ash content as low-cost feedstocks

dc.contributor.authorSaad, Victoria
dc.contributor.authorGutschmann, Björn
dc.contributor.authorGrimm, Thomas
dc.contributor.authorWidmer, Torsten
dc.contributor.authorNeubauer, Peter
dc.contributor.authorRiedel, Sebastian L.
dc.date.accessioned2021-03-12T07:39:29Z
dc.date.available2021-03-12T07:39:29Z
dc.date.issued2020-12-26
dc.description.abstractObjective: The rapid accumulation of crude-oil based plastics in the environment is posing a fundamental threat to the future of mankind. The biodegradable and bio-based polyhydroxyalkanoates (PHAs) can replace conventional plastics, however, their current production costs are not competitive and therefore prohibiting PHAs from fulfilling their potential. Results: Different low-quality animal by-products, which were separated by thermal hydrolysis into a fat-, fat/protein-emulsion- and mineral-fat-mixture- (material with high ash content) phase, were successfully screened as carbon sources for the production of PHA. Thereby, Ralstonia eutropha Re2058/pCB113 accumulated the short- and medium-chain-length copolymer poly(hydroxybutyrate- co -hydroxyhexanoate) [P(HB- co -HHx)]. Up to 90 wt% PHA per cell dry weight with HHx-contents of 12–26 mol% were produced in shake flask cultivations. Conclusion: In future, the PHA production cost could be lowered by using the described animal by-product streams as feedstock.en
dc.description.sponsorshipTU Berlin, Open-Access-Mittel – 2020en
dc.description.sponsorshipBMBF, 031B0798A, Bioökonomie International 2017: PHABio-up - Polyhydroxyalkanoate Biopolymere aus tierischen Abfallfetten: Scale-up zur Realisierung einer industriellen Produktionen
dc.description.sponsorshipBMBF, 031B0798C, Bioökonomie International 2017: PHABio-up - Polyhydroxyalkanoate Biopolymere aus tierischen Abfallfetten: Scale-up zur Realisierung einer industriellen Produktion - Teilvorhaben: Feedstock und Produktextraktionen
dc.identifier.eissn1573-6776
dc.identifier.issn0141-5492
dc.identifier.urihttps://depositonce.tu-berlin.de/handle/11303/12816
dc.identifier.urihttp://dx.doi.org/10.14279/depositonce-11616
dc.language.isoen
dc.relation.ispartof10.14279/depositonce-16758
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc570 Biowissenschaften; Biologieen
dc.subject.otherralstonia eutrophaen
dc.subject.otheranimal by-productsen
dc.subject.otherfat/protein-emulsionen
dc.subject.otherlow-cost feedstocksen
dc.subject.othermedium-chain-length PHAen
dc.subject.otherP(HB-co-HHx)en
dc.titleLow-quality animal by-product streams for the production of PHA-biopolymers: fats, fat/protein-emulsions and materials with high ash content as low-cost feedstocksen
dc.typeArticleen
dc.type.versionpublishedVersionen
dcterms.bibliographicCitation.doi10.1007/s10529-020-03065-yen
dcterms.bibliographicCitation.journaltitleBiotechnology Lettersen
dcterms.bibliographicCitation.originalpublishernameSpringerNatureen
dcterms.bibliographicCitation.originalpublisherplaceLondon [u.a.]en
tub.accessrights.dnbfreeen
tub.affiliationFak. 3 Prozesswissenschaften::Inst. Biotechnologie::FG Bioverfahrenstechnikde
tub.affiliation.facultyFak. 3 Prozesswissenschaftende
tub.affiliation.groupFG Bioverfahrenstechnikde
tub.affiliation.instituteInst. Biotechnologiede
tub.publisher.universityorinstitutionTechnische Universität Berlinen

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