Identification of the amino acid labionin and its desulfurised derivative in the type-III lantibiotic LabA2 by means of GC/MS

Pesic, AlexanderHenkel, MaikSüßmuth, Roderich D.2016-06-302016-06-3020111359-7345https://depositonce.tu-berlin.de/handle/11303/5734http://dx.doi.org/10.14279/depositonce-5354Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.A GC-MS method for the rapid and unambiguous identification of the amino acid labionin (Lab) occurring in type-III lantibiotics is presented. This method will constitute a valuable tool for the characterisation and structure elucidation of labyrinthopeptins and their differentiation from lanthionine-type lantibiotics.en540 Chemie und zugeordnete WissenschaftenIdentification of the amino acid labionin and its desulfurised derivative in the type-III lantibiotic LabA2 by means of GC/MSArticle1364-548X21603709