Wiedemann, DennisGrohmann, Andreas2016-09-132016-09-1320090932-0776https://depositonce.tu-berlin.de/handle/11303/5897http://dx.doi.org/10.14279/depositonce-5490The historical and recent literature describing synthetical pathways to the title compds. is comprehensively summarized and evaluated. Routes via 2,5-dioxoadipic acid or 2,5-dihydroxymuconic acid as intermediates could not be followed reproducibly. 3-Hydroxy-2-oxo-2H-pyran-6-carboxylic acid and Et 3-hydroxy-2-oxo-3-pyrroline-4-carboxylate (I) were fully characterized by spectroscopic methods and single-crystal x-ray diffraction. Both compds. have an enolic structure in soln. as well as in the solid state. A recently published ring-closing metathesis (RCM) protocol to a deriv. of the first title compd. was unproductive in the authors' hands. The authors present a new two-step synthesis of the similarly substituted 5-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamide (II) using succinyl cyanide. The product was identified and characterized by spectroscopic methods and x-ray crystallog. [on SciFinder(R)]en540 Chemie und zugeordnete Wissenschaftenlanthanoid chelators1,2-HOPO2,5-Dioxohexanedioic acid2,5-Dioxohexanedinitrile5-Hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamideArticle1865-7117