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Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

Jakoblinnert, Andre; Mladenov, Radoslav; Paul, Albert; Sibilla, Fabrizio; Schwaneberg, Ulrich; Ansorge-Schumacher, Marion B.; María, Pablo Domínguez de

The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (aw). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.
Published in: Chemical communications, 10.1039/c1cc14097c, Royal Society of Chemistry
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