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Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

Jakoblinnert, Andre; Mladenov, Radoslav; Paul, Albert; Sibilla, Fabrizio; Schwaneberg, Ulrich; Ansorge-Schumacher, Marion B.; María, Pablo Domínguez de

FG Technische Chemie

The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (aw). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.
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  • This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.